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Peptide record

TPDB62018

Bac7 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB62018
Bac7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: PMO Ivs2-654 Attached
Sequence
GGKGGRRIRPRPPRLPRPRPRPLPFPRPG
Physicochemical Analysis
C147H249N57O30
ANDCEQHMSTWYV
P
3294.96
13.30
10
0
4
+10
10.27
-1.638
40.34
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
1
I
2
L
1
K
0
M
1
F
10
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 1 L: 2 K: 1 M: 0 F: 1 P: 10 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
29
C147H249N57O30
3294.96
13.30
+10
10.27
-1.638
Free
L
Cationic
Linear
PMO Ivs2-654 Attached
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
PMO IVS2-654-Biotin
Cytoplasm
L and D-peptides shared nearly identical PMO delivery activities
Endocytosis
In vitro
CHHHHHHHHHTTTSCC
Additional Detail Fields 1 fields
CHHHHHHHHHTTTSCC