Back to search

Peptide record

TPDB62015

Hel11-7 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62015
Hel11-7
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: PMO Ivs2-654 Attached
Sequence
GGKGGLLKLLLKLWKKLLKLLK
Physicochemical Analysis
C121H218N30O23
ARNDCEQHIMFPSTYV
L
2461.25
11.29
7
0
11
+7
-0.48
0.373
177.27
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
223.46
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
10
L
7
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 10 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
22
C121H218N30O23
2461.25
11.29
+7
-0.48
0.373
Free
L
Amphipathic
Linear
PMO Ivs2-654 Attached
NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
PMO IVS2-654-Biotin
Cytoplasm
L and D-peptides shared nearly identical PMO delivery activities
Endocytosis
In vitro
CCSSCSSSSCCCCSCCCCC
Additional Detail Fields 1 fields
CCSSCSSSSCCCCSCCCCC