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Peptide record

TPDB62009

DPV6 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB62009
DPV6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: PMO Ivs2-654 Attached
Sequence
GGKGGGRPRESGKKRKRKRLKP
Physicochemical Analysis
C102H189N43O26
ANDCQHIMFTWYV
GK
2433.90
12.59
11
1
1
+10
12.54
-2.364
17.73
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
1
E
0
Q
6
G
0
H
0
I
1
L
6
K
0
M
0
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 6 H: 0 I: 0 L: 1 K: 6 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C102H189N43O26
2433.90
12.59
+10
12.54
-2.364
Free
L
Amphipathic
Linear
PMO Ivs2-654 Attached
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Amphipathic
Protein derived
PMO IVS2-654-Biotin
Cytoplasm
L and D-peptides shared nearly identical PMO delivery activities
Endocytosis
In vitro