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Peptide record

TPDB62008

PNT-GG 3 Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB62008
PNT-GG 3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acylation
Sequence
GGIWFQNRRM-NH2
Physicochemical Analysis
C56H85N19O13S1
ADCEHLKPSTYV
RG
1264.47
12.40
2
0
4
+2
-0.88
-0.850
39.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
434.96
2
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
1
Q
2
G
0
H
1
I
0
L
0
K
1
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 0 K: 0 M: 1 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C56H85N19O13S1
1264.47
12.40
+2
-0.88
-0.850
Amidation
L
Cationic
Linear
Acylation
NCC(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Transparent Porcine Corneas(Isolated From Fresh Pig Eyes)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
FAM-labelled at C terminus
Apparent permeability coefficients=0.44 ± 0.50 × 10−6 (cm/s) (Donor concentration-100microMolar)
Ex vivo
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC