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Peptide record

TPDB62005

T7-TAT Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB62005
T7-TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
GGGSMLGISYGRKKRRQRRRPPQT
Physicochemical Analysis
C114H200N46O31S1
ANDCEHFWV
R
2743.19
12.71
8
0
4
+8
7.31
-1.683
32.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
54.32
6
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
2
Q
5
G
0
H
1
I
1
L
2
K
1
M
0
F
2
P
2
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 5 H: 0 I: 1 L: 1 K: 2 M: 1 F: 0 P: 2 S: 2 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
24
C114H200N46O31S1
2743.19
12.71
+8
7.31
-1.683
Free
L
Linear
Free
N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](Cc1[nH]cnc1)C(=O)NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Vero, Bhk-21, Mdck, Marc-145

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
T7-EEB phage
Cytoplasm
T7-EEB-Tat phage could successfully deliver EEB into eukaryotic cells
Endocytosis
In vitro
CCCTTGGGGCSCCCC
Additional Detail Fields 1 fields
CCCTTGGGGCSCCCC