Back to search

Peptide record

TPDB61994

RFWF9 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61994
RFWF9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: G4 linker N-terminal: Biotinylation
Sequence
GGGGRRFWRRFRR-NH2
Physicochemical Analysis
C73H114N32O14
ANDCEQHILKMPSTYV
R
1663.91
13.10
6
0
3
+6
0.79
-1.838
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
330.55
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C73H114N32O14
1663.91
13.10
+6
0.79
-1.838
Amidation
G4 linker
L
Linear
Biotinylation
N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Much less internalized (~ 1 pmol or less) than RW9 (~ 10 pmol) shows about a ten-fold decrease
In vitro
CTTCCCTTSCCC
Additional Detail Fields 1 fields
CTTCCCTTSCCC