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Peptide record

TPDB61989

POD Cell-penetrating Peptides standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB61989
POD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 35-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Conjugation with GFP
Sequence
GGGARKKAAKAARKKAAKAARKKAAKAARKKAAKA
Physicochemical Analysis
C150H283N59O36
NDCEQHILMFPSTWYV
A
3489.27
12.91
16
0
16
+16
12.43
-1.063
45.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
16
A
4
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
12
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 16 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 12 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
35
C150H283N59O36
3489.27
12.91
+16
12.43
-1.063
Conjugation with GFP
L
Linear
Free
NCC(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human embryonic retinoblasts, A549

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Protein (GFP)
Punctate pattern (vesicles)
Endocytic pathways but more than one mechanism may possible
In vitro
CCCCTTCSHHHHHHHHHHHHHHHHHHHHTTSCCCC
Additional Detail Fields 1 fields
CCCCTTCSHHHHHHHHHHHHHHHHHHHHTTSCCCC