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Peptide record

TPDB61967

AHRR(8-24) Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61967
AHRR(8-24)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
GECTYAGRKRRRPLQK-NH2
Physicochemical Analysis
C80H139N31O22S1
NDHIMFSWV
R
1919.24
11.34
6
1
3
+5
6.52
-1.819
30.63
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
77.63
4
Residue Composition
number
1
A
4
R
0
N
0
D
1
C
1
E
1
Q
2
G
0
H
0
I
1
L
2
K
0
M
0
F
1
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 2 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
16
C80H139N31O22S1
1919.24
11.34
+5
6.52
-1.819
Amidation
L
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87, PC3, And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FAM-conjugated
Strongest and well dispersed fluorescent signal
In vitro
CCCSSSCCCCCCCC
Additional Detail Fields 1 fields
CCCSSSCCCCCCCC