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Peptide record

TPDB61951

MPG-NLS Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB61951
MPG-NLS
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Linker Di-Glycine
Sequence
GALFLGWLGAAGSTMGAPKSKRKVGGC
Physicochemical Analysis
C116H190N34O31S2
NDEQHIY
G
2621.11
10.83
4
0
11
+4
-1.04
0.230
68.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
209.83
4
Residue Composition
number
4
A
1
R
0
N
0
D
1
C
0
E
0
Q
7
G
0
H
0
I
3
L
3
K
1
M
1
F
1
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 7 H: 0 I: 0 L: 3 K: 3 M: 1 F: 1 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C116H190N34O31S2
2621.11
10.83
+4
-1.04
0.230
Free
Linker Di-Glycine
L
Linear
Free
NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HT-29-luc cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PNA
Endocytosis
In vitro
CCCCSSCCSSSTTTCSGGGGTTTTCCC
Additional Detail Fields 1 fields
CCCCSSCCSSSTTTCSGGGGTTTTCCC