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Peptide record

TPDB61948

MPG_FIT_PNA1 Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB61948
MPG_FIT_PNA1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-GALFLGFLGAAGSTMGAWSQPKKRKVC
Physicochemical Analysis
C126H201N35O32S2
NDEHIY
G
2782.32
10.83
4
0
12
+4
-1.61
0.233
68.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
197.68
5
Residue Composition
number
4
A
1
R
0
N
0
D
1
C
0
E
1
Q
5
G
0
H
0
I
3
L
3
K
1
M
2
F
1
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 5 H: 0 I: 0 L: 3 K: 3 M: 1 F: 2 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C126H201N35O32S2
2782.32
10.83
+4
-1.61
0.233
Free
L
Linear
Acetylation
NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
FIT-PNA1
Cytosol
In vitro
CCSCGGGGTCCSCCTTTSSSSCCCCCC
Additional Detail Fields 1 fields
CCSCGGGGTCCSCCTTTSSSSCCCCCC