Back to search

Peptide record

TPDB61946

P(alpha) Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61946
P(alpha)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Cysteamide group N-terminal: Acetylation
Sequence
Ac-GALFLAFLAAALSLMGLWSQPKKKRRV
Physicochemical Analysis
C140H230N38O31S1
NDCEHITY
L
2973.66
12.43
5
0
16
+5
-2.58
0.533
115.93
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
184.96
3
Residue Composition
number
5
A
2
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
6
L
3
K
1
M
2
F
1
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 6 K: 3 M: 1 F: 2 P: 1 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C140H230N38O31S1
2973.66
12.43
+5
-2.58
0.533
Cysteamide group
L
Amphipathic
Linear
Acetylation
NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
In vitro
CCCCHHHHHHHIIIIISTTCCSSSCCC
Additional Detail Fields 1 fields
CCCCHHHHHHHIIIIISTTCCSSSCCC