Back to search

Peptide record

TPDB61944

MPG-α Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61944
MPG-α
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-GALFLAAALSLMGLWSQPKKKRKV-NH2
Physicochemical Analysis
C122H205N33O28S1
NDCEHITY
L
2614.23
11.80
5
0
13
+5
-0.54
0.275
110.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
210.39
3
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
5
L
4
K
1
M
1
F
1
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 5 K: 4 M: 1 F: 1 P: 1 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
24
C122H205N33O28S1
2614.23
11.80
+5
-0.54
0.275
Amidation
L
Linear
Acetylation
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ht-1080 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Near-infrared fluorescent DY676 labelled cargos (BSA, monoclonal Ab)
Golgi/Late Endosomal Localization
MPGα resulted in high internalization levels
In vitro
CCSSSTTCCC
Additional Detail Fields 1 fields
CCSSSTTCCC