Back to search

Peptide record

TPDB61925

αAC(71–88)Antp Cell-penetrating Peptides standard
34 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61925
αAC(71–88)Antp
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 34-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Nanofiber
Sequence
FVIFLDVKHFSPEDLTVKRQIKIWFQNRRMKWKK
Physicochemical Analysis
C207H322N56O46S1
ACGY
K
4363.24
11.14
10
3
15
+6
5.82
-0.565
82.94
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
252.11
5
Residue Composition
number
0
A
3
R
1
N
2
D
0
C
1
E
2
Q
0
G
1
H
3
I
2
L
6
K
1
M
4
F
1
P
1
S
1
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 2 C: 0 E: 1 Q: 2 G: 0 H: 1 I: 3 L: 2 K: 6 M: 1 F: 4 P: 1 S: 1 T: 1 W: 2 Y: 0 V: 3
Chemical Descriptors
34
C207H322N56O46S1
4363.24
11.14
+6
5.82
-0.565
Free
Nanofiber
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Pc12 Cells

Assay & Model

Adult C57BL/6J mice (10-14-weeks)
Adult C57BL/6J mice (10-14-weeks)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
αAC(71–88) protein
Nanofibers could penetrate the BBB and be successfully delivered into brain parenchymal cells
In vitro and in vivo
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC