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Peptide record

TPDB61918

ARF(1-37) scr Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB61918
ARF(1-37) scr
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
FRVPLRIRPCVVAPRLVMVRHTFGRIARWVAGPLETR-NH2
Physicochemical Analysis
C197H326N64O42S2
NDQKSY
R
4327.28
12.62
9
1
18
+7
4.59
0.238
107.84
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
127.10
3
Residue Composition
number
3
A
8
R
0
N
0
D
1
C
1
E
0
Q
2
G
1
H
2
I
3
L
0
K
1
M
2
F
4
P
0
S
2
T
1
W
0
Y
6
V
Amino Acid Distribution
A: 3 R: 8 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 2 H: 1 I: 2 L: 3 K: 0 M: 1 F: 2 P: 4 S: 0 T: 2 W: 1 Y: 0 V: 6
Chemical Descriptors
37
C197H326N64O42S2
4327.28
12.62
+7
4.59
0.238
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7 and MDA MB 231

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein)
In vitro
CCCCCSSCCCSSCSSCCSCSSSHHHHTTTSSSSSCC
Additional Detail Fields 1 fields
CCCCCSSCCCSSCSSCCSCSSSHHHHTTTSSSSSCC