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Peptide record

TPDB61889

CDX Blood-Brain Barrier Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61889
CDX
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict Peptipedia CPPsite3.0
standard
No
A 16-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict, Peptipedia, and CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with CF Via GGG Linker
Sequence
FKESWREARGTRIERG
Physicochemical Analysis
C85H136N30O25
NDCQHLMPYV
R
1978.20
11.15
5
3
4
+2
7.12
-1.656
30.63
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
278.03
2
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
3
E
0
Q
2
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 3 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C85H136N30O25
1978.20
11.15
+2
7.12
-1.656
Free
L
Linear
Conjugated with CF Via GGG Linker
N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

hCMEC/D3 Cell

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
CF dye
Showed significantly higher permeability than FD-4
In vitro
CTTTTHHHHHHHHTTTCC
Additional Detail Fields 1 fields
CTTTTHHHHHHHHTTTCC