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Peptide record

TPDB61832

Tetrapeptide 1 Cell-penetrating Peptides standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB61832
Tetrapeptide 1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 4-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with CF
Sequence
ETWW
Physicochemical Analysis
C31H36N6O8
ARNDCQGHILKMFPSYV
W
620.66
3.29
0
1
2
-1
-1.54
-1.500
0.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
11000
1772.30
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
4
C31H36N6O8
620.66
3.29
-1
-1.54
-1.500
Free
L
Anionic
Linear
Conjugated with CF
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF7, HeLa, A549, U87, Hepg2 And B16F10 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Anionic
Synthetic
CF dye
Nucleus
99.4% median uptake value
Endocytosis
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC