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Peptide record

TPDB61803

BoNTA-ZFP3 ZFP3-BoNTA Cell-penetrating Peptides standard
84 amino acids
Basic Information
3D PDB MODEL
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TPDB61803
BoNTA-ZFP3 ZFP3-BoNTA
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 84-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
EKPYKCPECGKSFSASAALVAHQRTHTGEKPYKCPECGKSFSASAALVAHQRTHTGEKPYKCPECGKSFSASAALVAHQRTHTG
Physicochemical Analysis
C387H605N117O118S6
NDIMW
A
8977.13
9.11
18
6
24
+6
24.57
-0.686
38.57
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
4845
53.97
27
Residue Composition
number
12
A
3
R
0
N
0
D
6
C
6
E
3
Q
6
G
6
H
0
I
3
L
9
K
0
M
3
F
6
P
9
S
6
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 12 R: 3 N: 0 D: 0 C: 6 E: 6 Q: 3 G: 6 H: 6 I: 0 L: 3 K: 9 M: 0 F: 3 P: 6 S: 9 T: 6 W: 0 Y: 3 V: 3
Chemical Descriptors
84
C387H605N117O118S6
8977.13
9.11
+6
24.57
-0.686
Free
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NC.C(O)N[C@@H](CO)C(=O)O NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

N2A Cells

Assay & Model

Eight week old, C57BL/6J female mice (17–22 g)
Eight week old, C57BL/6J female mice (17–22 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Botulinum neurotoxin serotype A (BoNTA)
In vitro and in vivo
CBSCCCTTSCCBSSCCSSSSSSCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

N2A Cells

Assay & Model

Eight week old, C57BL/6J female mice (17–22 g)
Eight week old, C57BL/6J female mice (17–22 g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Protein derived
Botulinum neurotoxin serotype A (BoNTA)
In vitro and in vivo
CCCCCCCCCCCCC
Additional Detail Fields 1 fields
CBSCCCTTSCCBSSCCSSSSSSCC CCCCCCCCCCCCC