Back to search

Peptide record

TPDB61787

E3-MP Cell-penetrating Peptides modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61787
E3-MP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 17-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
EEEINWKGIAAJAKKLL-NH2
Physicochemical Analysis
C83H137N21O24
RDCQHMFPSTYV
AEK
1813.13
7.13
3
3
8
+0
5.36
-0.294
109.41
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
5500
303.34
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
3
E
0
Q
1
G
0
H
2
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 3 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C83H137N21O24
1813.13
7.13
+0
5.36
-0.294
Amidation
L
Cationic and amphiphilic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic and amphiphilic
Synthetic
FITC-dextran
Cytosol
At 100 microm, FITC- dextran was more efficiently delivered to the cytosol compared with 3 microm MP.
In vitro