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Peptide record

TPDB61778

Glu-Lys Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB61778
Glu-Lys
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with FITC
Sequence
EEEAAKKK
Physicochemical Analysis
C39H69N11O15
RNDCQGHILMFPSTWYV
EK
932.04
7.13
3
3
2
+0
8.69
-2.325
25.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
3
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 3 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C39H69N11O15
932.04
7.13
+0
8.69
-2.325
Conjugation with FITC
L
Linear
Free
N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

DU-145 and LNCaP

Source & Reference

CPPsite3.0
CPPsite3
US 20100137187

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (FITC)
Cytoplasm
Lower than Glu-Oct-6 but higher than Oct-6
Receptor-independent non-endocytic pathway
In vitro
CTTTTCCC
Additional Detail Fields 1 fields
CTTTTCCC