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Peptide record

TPDB61763

RSG 1.2 Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB61763
RSG 1.2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation
Sequence
DRRRRGSRPSGAERRRRRAAAA-NH2
Physicochemical Analysis
C99H182N52O29
NCQHILKMFTWYV
R
2564.87
12.77
10
2
5
+8
11.23
-2.136
22.73
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
5
A
10
R
0
N
1
D
0
C
1
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 10 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C99H182N52O29
2564.87
12.77
+8
11.23
-2.136
Amidation
L
Cationic
Linear
Biotinylation
N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

EBTr cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060223752

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Biotin
In vitro
CCSTTCCCCCCTHHHHTTTCCC
Additional Detail Fields 1 fields
CCSTTCCCCCCTHHHHTTTCCC