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Peptide record

TPDB61757

Secretory leukoprotease inhibitor derived PTD Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB61757
Secretory leukoprotease inhibitor derived PTD
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with FITC
Sequence
DPVDTPNPTRRKPGK
Physicochemical Analysis
C71H120N24O23
ACEQHILMFSWY
P
1677.88
10.57
4
2
1
+2
8.64
-2.087
19.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
2
R
1
N
2
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
4
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 2 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 4 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C71H120N24O23
1677.88
10.57
+2
8.64
-2.087
L
Linear
Conjugation with FITC
N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

P5 DRG neurons

Source & Reference

CPPsite3.0
CPPsite3
US20110107443

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (FITC)
Nucleus
Non-endocytic mechanism
In vitro
CGGGSSCCTTTCSCC
Additional Detail Fields 1 fields
CGGGSSCCTTTCSCC