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Peptide record

TPDB61740

hCT(15–32) Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB61740
hCT(15–32)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
DFNKFHTFPQTAIGVGAP-NH2
Physicochemical Analysis
C91H131N23O25
RCELMSWY
F
1947.18
7.81
2
1
7
+0
1.41
-0.128
48.89
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
0
R
1
N
1
D
0
C
0
E
1
Q
2
G
1
H
1
I
0
L
1
K
0
M
3
F
2
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 1 L: 0 K: 1 M: 0 F: 3 P: 2 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C91H131N23O25
1947.18
7.81
+0
1.41
-0.128
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MDCK, Calu-3 and TR146 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein)
In vitro
CCSSSCCCCTTSSSCCC
Additional Detail Fields 1 fields
CCSSSCCCCTTSSSCCC