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Peptide record

TPDB61735

RMNE3 (DualPep-Shine) Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB61735
RMNE3 (DualPep-Shine)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: FITC-conjugated
Sequence
DEQERRRRRGRTR
Physicochemical Analysis
C67H123N35O22
ANCHILKMFPSWYV
R
1770.94
12.28
7
3
0
+4
11.67
-3.585
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
7
R
0
N
1
D
0
C
2
E
1
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 1 C: 0 E: 2 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C67H123N35O22
1770.94
12.28
+4
11.67
-3.585
Free
FITC-conjugated
L
Linear
Free
N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HaCaT And B16F12 cell

Assay & Model

3D human skin (Neoderm-ME)
3D human skin (Neoderm-ME)

Source & Reference

CPPsite3.0
CPPsite3
Composition comprising a peptide having skin whitening activity (application number: 10-2022-0109704 country: the Republic of Korea)

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Leptin and FITC dye
Cytosol and Nucleus
RMNE1 and RMNE3 showed similar penetration abilities
In vitro and ex vivo
CCHHHHHTCCCCC
Additional Detail Fields 1 fields
CCHHHHHTCCCCC