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Peptide record

TPDB61691

EGFP-VP_22 Cell-penetrating Peptides standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB61691
EGFP-VP_22
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 35-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugated with EGFP
Sequence
DAATARGRGRSAASRPTERPRAPARSASRPRRPVD
Physicochemical Analysis
C151H263N65O48
NCQHILKMFWY
R
3757.16
12.58
10
3
9
+7
14.36
-1.437
31.14
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
6
Residue Composition
number
8
A
10
R
0
N
2
D
0
C
1
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
5
P
4
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 8 R: 10 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 5 S: 4 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
35
C151H263N65O48
3757.16
12.58
+7
14.36
-1.437
Free
L
Amphipathic
Linear
Conjugated with EGFP
N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mouse macrophage-like cell line J774 A.3

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Protein (eGFP)
Cytoplasm
Showed increased uptake efficiency
In vitro
CCSSSCSSTTCCCCCCTTSCCCCCSSCCCCCSSCC
Additional Detail Fields 1 fields
CCSSSCSSTTCCCCCCTTSCCCCCSSCCCCCSSCC