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Peptide record

TPDB61683

BTAT Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB61683
BTAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CYGRKKRRQRRRCYGRKKRRQRRRC
Physicochemical Analysis
C137H249N67O30S3
ANDEHILMFPSTWV
R
3411.10
12.41
16
0
2
+16
12.26
-2.900
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
3105
91.03
7
Residue Composition
number
0
A
12
R
0
N
0
D
3
C
0
E
2
Q
2
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 12 N: 0 D: 0 C: 3 E: 0 Q: 2 G: 2 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
25
C137H249N67O30S3
3411.10
12.41
+16
12.26
-2.900
Free
L
Cationic
Branched
Free
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Branched L Cationic
Synthetic
plasmid green fluorescence protein (pGFP)
BTAT/pGFP complex showed 40-fold higher transfection efficiency than TAT and mTAT complexes
In vitro
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC