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Peptide record

TPDB61631

(C(WR)5C) Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB61631
(C(WR)5C)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CWRWRWRWRWRC
Physicochemical Analysis
C91H122N32O13S2
ANDEQGHILKMFPSTYV
RW
1936.30
12.23
5
0
5
+5
-5.68
-1.833
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
27625
1426.69
2
Residue Composition
number
0
A
5
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
12
C91H122N32O13S2
1936.30
12.23
+5
-5.68
-1.833
Free
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CCRF-CEM And MDA-MB-231 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
F′-GpYEEI phosphopeptide
c[C(WR)4C]) did not show any significant improvement
In vitro
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC