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Peptide record

TPDB61618

AlkCWK13 (SEQ ID NO:6) Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB61618
AlkCWK13 (SEQ ID NO:6)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-CWKKKKKKKKKKKKK
Physicochemical Analysis
C92H173N29O16S1
ARNDEQGHILMFPSTYV
K
1973.63
11.25
13
0
1
+13
10.78
-3.273
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5500
278.67
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
13
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 13 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C92H173N29O16S1
1973.63
11.25
+13
10.78
-3.273
Free
L
Cationic
Linear
Acetylation
N[C@@H](CS)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HepG2 and COS-7 cells

Source & Reference

CPPsite3.0
CPPsite3
US 7112442

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Nucleic acid
In vitro
CCCCCGGGGGCCCCC
Additional Detail Fields 1 fields
CCCCCGGGGGCCCCC