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Peptide record

TPDB61610

S41 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB61610
S41
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with FITC
Sequence
CVQWSLLRGYQPC
Physicochemical Analysis
C69H105N19O18S2
ANDEHIKMFT
CQL
1552.83
8.28
1
0
5
+1
-1.76
0.023
82.31
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7115
458.20
6
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
2
Q
1
G
0
H
0
I
2
L
0
K
0
M
0
F
1
P
1
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
13
C69H105N19O18S2
1552.83
8.28
+1
-1.76
0.023
L
Linear
Conjugation with FITC
N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

N2A and CGNs cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (FITC)
Co-localizes with lipid rafts
Lipid-raft mediated endocytosis
In vitro
CCCCCSSSSCCCC
Additional Detail Fields 1 fields
CCCCCSSSSCCCC