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Peptide record

TPDB61609

DPV1048 Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB61609
DPV1048
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
CVKRGLKLRHVRPRVTRDV
Physicochemical Analysis
C98H178N38O23S1
ANEQIMFSWY
R
2288.79
12.24
8
1
6
+6
7.74
-0.674
102.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
5
R
0
N
1
D
1
C
0
E
0
Q
1
G
1
H
0
I
2
L
2
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 2 K: 2 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
19
C98H178N38O23S1
2288.79
12.24
+6
7.74
-0.674
L
Linear
N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, PC-3, NCI-H460 and MDA-MB-231

Source & Reference

CPPsite3.0
CPPsite3
US 20090186802

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nucleic acid (siRNA)
Cytoplasm
Endocytic pathway
In vitro
CCCCCCSSSSCCCCSCCC
Additional Detail Fields 1 fields
CCCCCCSSSSCCCCSCCC