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Peptide record

TPDB61600

LI Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB61600
LI
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Addition of Cysteine
Sequence
CTSTTAKRKKRKLK
Physicochemical Analysis
C69H133N25O19S1
NDEQGHIMFPWYV
K
1649.03
11.68
7
0
2
+7
6.15
-1.664
35.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
2
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
1
L
5
K
0
M
0
F
0
P
1
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 5 M: 0 F: 0 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C69H133N25O19S1
1649.03
11.68
+7
6.15
-1.664
Free
L
Linear
Addition of Cysteine
N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Malignant human glioma cells U87MG and COS-7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nucleic acid (Plasmid DNA and siRNA)
In vitro
CCCCCCTTSCSCCC
Additional Detail Fields 1 fields
CCCCCCTTSCSCCC