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Peptide record

TPDB61594

1A Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB61594
1A
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
CSSLDEPGRGGFSSESKV-NH2
Physicochemical Analysis
C75H120N22O30S1
ANQHIMTWY
S
1841.97
4.44
2
3
3
-1
6.34
-0.689
37.78
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
0
A
1
R
0
N
1
D
1
C
2
E
0
Q
3
G
0
H
0
I
1
L
1
K
0
M
1
F
1
P
5
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 1 E: 2 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 1 M: 0 F: 1 P: 1 S: 5 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C75H120N22O30S1
1841.97
4.44
-1
6.34
-0.689
Amidation
L
Cationic
Linear
Conjugation with fluorescein
N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

RBL-2H3 cells, CHO-K1

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (Fluorescein)
Vesicles
Non-endocytic mechanism
In vivo
CCSSCCTTTTSCCSCCCC
Additional Detail Fields 1 fields
CCSSCCTTTTSCCSCCCC