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Peptide record

TPDB61592

P16/16 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB61592
P16/16
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
CSPQYTIIADAGDFYLHPSYYMLRKRRKR
Physicochemical Analysis
C160H246N46O42S2
NEWV
RY
3550.12
10.00
7
2
12
+4
3.09
-0.800
60.69
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5960
167.88
9
Residue Composition
number
2
A
4
R
0
N
2
D
1
C
0
E
1
Q
1
G
1
H
2
I
2
L
2
K
1
M
1
F
2
P
2
S
1
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 2 C: 1 E: 0 Q: 1 G: 1 H: 1 I: 2 L: 2 K: 2 M: 1 F: 1 P: 2 S: 2 T: 1 W: 0 Y: 4 V: 0
Chemical Descriptors
29
C160H246N46O42S2
3550.12
10.00
+4
3.09
-0.800
Free
L
Linear
Biotinylation
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa-S3 Cells And Hacat Cells

Assay & Model

HPV16:pClucF PsV infected mice
HPV16:pClucF PsV infected mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Cytoplasm
bP16/16 was localized to large cytoplasmic puncta superimposed on a more diffuse cytoplasmic distribution
In vitro and in vivo
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC