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Peptide record

TPDB61569

L-dodecaarginine Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB61569
L-dodecaarginine
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Addition of Cysteine Chemical: Palmitic acid via a Gly-Ser-Ser-Gly (GSSG) linker N-terminal: Addition of Cysteine
Sequence
CRRRRRRRRRRRRC
Physicochemical Analysis
C78H156N50O15S2
ANDEQGHILKMFPSTWYV
R
2098.54
12.88
12
0
0
+12
9.24
-3.500
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
5.96
2
Residue Composition
number
0
A
12
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 12 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C78H156N50O15S2
2098.54
12.88
+12
9.24
-3.500
Addition of Cysteine
Palmitic acid via a Gly-Ser-Ser-Gly (GSSG) linker
L
Cationic
Cyclic
Addition of Cysteine
N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L Cationic
Synthetic
FITC-HSA
In vitro
CCCCCCGGGGGSSCC
Additional Detail Fields 1 fields
CCCCCCGGGGGSSCC