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Peptide record

TPDB61552

Peptide 8 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB61552
Peptide 8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CRRRRFWQCTRV
Physicochemical Analysis
C70H115N29O15S2
ANDEGHILKMPSY
R
1666.99
12.23
5
0
3
+5
1.38
-1.300
24.17
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
337.43
4
Residue Composition
number
0
A
5
R
0
N
0
D
2
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C70H115N29O15S2
1666.99
12.23
+5
1.38
-1.300
Free
L
Amphipathic
Cyclic
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Cyclic L Amphipathic
Synthetic
FITC labelled
Cytoplasm
Peptide 8 was readily cell permeable resulted in intense and diffuse fluorescence throughout the entire cell
In vitro