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Peptide record

TPDB61546

CPP12 Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB61546
CPP12
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 9-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with TAMRA
Sequence
CRRGRRPDC
Physicochemical Analysis
C41H75N21O12S2
ANEQHILKMFSTWYV
R
1118.30
10.75
4
1
0
+3
4.45
-2.056
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
11.18
2
Residue Composition
number
0
A
4
R
0
N
1
D
2
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C41H75N21O12S2
1118.30
10.75
+3
4.45
-2.056
Conjugated with TAMRA
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=NC=NC1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Dh5Α

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
TAMRA dye
Cytoplasm
Penetration efficiency- 783.847044875A.U.
In vitro
CCCCC
Additional Detail Fields 1 fields
CCCCC