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Peptide record

TPDB61542

Reduced linear penetratin Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB61542
Reduced linear penetratin
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Biotinylation (Labeled with Biotinyl-Ahx)
Sequence
CRQIKIWFPNRRMKWKKC
Physicochemical Analysis
C110H177N35O21S3
ADEGHLSTYV
K
2422.02
11.53
7
0
6
+7
1.68
-1.156
43.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
11125
459.33
4
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
1
Q
0
G
0
H
2
I
0
L
4
K
1
M
1
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 0 K: 4 M: 1 F: 1 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
18
C110H177N35O21S3
2422.02
11.53
+7
1.68
-1.156
L
Amphipathic
Linear
Biotinylation (Labeled with Biotinyl-Ahx)
N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HaCat/ A549 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
Biotin
Non-endocytic mechanism
In vitro
CCSCCSCCCSSCCSSCCC
Additional Detail Fields 1 fields
CCSCCSCCCSSCCSSCCC