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Peptide record

TPDB61523

linear (CR)3 Cell-penetrating Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB61523
linear (CR)3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 6-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CRCRCR
Physicochemical Analysis
C27H53N15O7S3
ANDEQGHILKMFPSTWYV
RC
795.99
9.30
3
0
0
+3
1.71
-1.000
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
15.70
3
Residue Composition
number
0
A
3
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C27H53N15O7S3
795.99
9.30
+3
1.71
-1.000
Free
L
Cationic
Linear
Free
N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)O N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Sk-Ov-3 And CCRF-CEM Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
CF-labelled 3TC
l(CR)3 did not enhance the cargo’s uptake.
In vitro
CCCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Sk-Ov-3 And CCRF-CEM Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L Cationic
Synthetic
CF-labelled GpYEEI
l(CR)3 was unable to enhance the cellular uptake of F0-GpYEEI
In vitro
CCCSSSCSCC
Additional Detail Fields 1 fields
CCCC CCCSSSCSCC