Back to search

Peptide record

TPDB61509

LP-P2 Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61509
LP-P2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CLRRLRRRLLRLWRLRRR
Physicochemical Analysis
C110H203N49O19S1
ANDEQGHIKMFPSTYV
R
2548.20
13.00
10
0
7
+10
2.65
-1.144
130.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5500
215.84
1
Residue Composition
number
0
A
10
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
6
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C110H203N49O19S1
2548.20
13.00
+10
2.65
-1.144
Free
L
Cationic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

P. aeruginosa and MRSA

Assay & Model

BALb/c mice (8 weeks, 18–20 g, male)
BALb/c mice (8 weeks, 18–20 g, male)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Synthetic
Liposomes (LP)
Membrane damage
In vitro and in vivo