Peptide record

TPDB61502

Cys-pVEC (9b) Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB61502
Cys-pVEC (9b)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Addition of Cysteine
Sequence
CLLIILRRRIRKQAHAHSK
Physicochemical Analysis
C101H182N38O22S1
NDEGMFPTWYV
R
2312.86
12.41
8
0
8
+6
4.66
-0.289
133.68
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
4
R
0
N
0
D
1
C
0
E
1
Q
0
G
2
H
3
I
3
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 2 I: 3 L: 3 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C101H182N38O22S1
2312.86
12.41
+6
4.66
-0.289
Free
L
Amphipathic
Linear
Addition of Cysteine
N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mkn-28, Caco-2 , Ht-29

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Gemcitabine
In vitro
CCCSSCCCC
Additional Detail Fields 1 fields
CCCSSCCCC