Back to search

Peptide record

TPDB61497

hCT(9-32) Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61497
hCT(9-32)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: CAAKA spacer N-terminal: Addition of Cysteine
Sequence
CLGTYTQDFNKFHTFPQTAIGVGAP
Physicochemical Analysis
C124H181N31O36S1
REMSW
T
2714.05
7.15
2
1
9
+0
0.54
-0.104
50.80
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
54.90
9
Residue Composition
number
2
A
0
R
1
N
1
D
1
C
0
E
2
Q
3
G
1
H
1
I
1
L
1
K
0
M
3
F
2
P
0
S
4
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 1 E: 0 Q: 2 G: 3 H: 1 I: 1 L: 1 K: 1 M: 0 F: 3 P: 2 S: 0 T: 4 W: 0 Y: 1 V: 1
Chemical Descriptors
25
C124H181N31O36S1
2714.05
7.15
+0
0.54
-0.104
Free
CAAKA spacer
L
Linear
Addition of Cysteine
N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Drug Resistant Melanoma (A375 And A375-R), Mesothelioma (Msto And Msto-R), And Glioma (Rat 9L And 9L-R, And Human U87 And Ln18) Cell Lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Photoluminescent multi-shelled quantum dot (QD)
Cytoplasm and Endosomes
Cell specific internalization
In vitro
CTTTSCCCCHHHHHTGGGGTC
Additional Detail Fields 1 fields
CTTTSCCCCHHHHHTGGGGTC