Back to search

Peptide record

TPDB61492

Ginsentide TP1 Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61492
Ginsentide TP1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CKSGGAWCGFDPHGCCGNCGCLVGFCYGTGC
Physicochemical Analysis
C126H180N36O38S8
REQIM
G
3063.51
6.68
2
1
7
-0
-3.22
0.400
25.16
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7490
244.49
12
Residue Composition
number
1
A
0
R
1
N
1
D
8
C
0
E
0
Q
9
G
1
H
0
I
1
L
1
K
0
M
2
F
1
P
1
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 1 C: 8 E: 0 Q: 0 G: 9 H: 1 I: 0 L: 1 K: 1 M: 0 F: 2 P: 1 S: 1 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
31
C126H180N36O38S8
3063.51
6.68
-0
-3.22
0.400
Free
L
Hydrophobic
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HUVEC-Cs Cells

Assay & Model

Male ICR mice (23-25 g body weight)
Male ICR mice (23-25 g body weight)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Synthetic
Cy3 on lysine
Cy3-TP1 shows successful internalization into HUVEC-CS cells
Endocytosis
In vitro and in vivo
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC