Peptide record

TPDB61479

BP100 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB61479
BP100
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: MAL-TEG-(KH)14 micelles N-terminal: Acetylation
Sequence
Ac-CKKLFKKILKYL-NH2
Physicochemical Analysis
C75H129N17O14S1
ARNDEQGHMPSTWV
K
1525.01
10.48
5
0
6
+5
0.65
0.033
130.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
97.70
2
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
1
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C75H129N17O14S1
1525.01
10.48
+5
0.65
0.033
Amidation
MAL-TEG-(KH)14 micelles
L
Amphipathic
Linear
Acetylation
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Seedlings Of Arabidopsis Thaliana

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
pDNA (p35S-Nluc-tNOS)
Tat-MC and UM-MC did not significantly differ in efficiency
In vitro
CCSSCCSSCC
Additional Detail Fields 1 fields
CCSSCCSSCC