Back to search

Peptide record

TPDB61476

ATS-9R Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61476
ATS-9R
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: FITC-conjugated NPs
Sequence
CKGGRAKDRRRRRRRRRC
Physicochemical Analysis
C89H172N50O21S2
NEQHILMFPSTWYV
R
2342.79
12.58
12
1
1
+11
10.68
-2.794
5.56
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
5.34
2
Residue Composition
number
1
A
10
R
0
N
1
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 10 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C89H172N50O21S2
2342.79
12.58
+11
10.68
-2.794
Free
FITC-conjugated NPs
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

3T3-L1 Pre-Adipocytes And Mature Adipocytes

Assay & Model

HFD-induced Six-wk-old male C57BL/6J mice.
HFD-induced Six-wk-old male C57BL/6J mice.

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Fusogenic
Cy5.5 fluorescent-labeled dCas9/sgFabp4
Cytoplasm
The percentage of cells transfected with (dCas9/sgFabp4) + ATS-9R oligoplexes was 99%.
In vitro and in vivo
CCCSSCCGGGTCCCCC
Additional Detail Fields 1 fields
CCCSSCCGGGTCCCCC