Back to search

Peptide record

TPDB61475

cysteine modified F3 F3 Peptide Cell-penetrating Peptides Tumor-homing Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61475
cysteine modified F3 F3 Peptide
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia PerseuCPP TumorHoPe2.0
standard
No
A 32-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CPPsite3.0, Peptipedia, PerseuCPP, and other sources, with an available 3D structural model.
Sequence
CKDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
Physicochemical Analysis
C155H268N50O42S1
NGHIMFTWYV
KP
3536.20
10.96
11
3
6
+8
18.41
-1.806
27.81
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
5
A
3
R
0
N
1
D
1
C
2
E
1
Q
0
G
0
H
0
I
1
L
8
K
0
M
0
F
8
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 3 N: 0 D: 1 C: 1 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 8 M: 0 F: 0 P: 8 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
32
C155H268N50O42S1
3536.20
10.96
+8
18.41
-1.806
Free
L
Cationic
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](/C=C\C(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat C6 glioma

Assay & Model

Balb/c nude mice bearing intracranial C6 glioma
Balb/c nude mice bearing intracranial C6 glioma

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Nanoparticle
In vitro and in vivo
CCCCGGGTSSCCCCCCCCCCCCSGGGTCCCCC
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Targeting

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease inhibitor:protease sensitive expression system, composition and methods for improving the therapeutic activity and specificity of proteins delivered by bacteria
2022
US 11219671 B1
US 11219671 B1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Salmonella typhimurium
Phage display library
Ph.D-7 Phage Display
Additional Detail Fields 3 fields
CCCCGGGTSSCCCCCCCCCCCCSGGGTCCCCC
Salmonella typhimurium
Ph.D-7 Phage Display