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Peptide record

TPDB61465

HR9 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB61465
HR9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
CHHHHRRRRRRRRRHHHHHC
Physicochemical Analysis
C114H183N65O21S2
ANDEQGILKMFPSTWYV
RH
2864.25
12.70
18
0
0
+10
15.45
-3.215
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
4.36
2
Residue Composition
number
0
A
9
R
0
N
0
D
2
C
0
E
0
Q
0
G
9
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 9 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C114H183N65O21S2
2864.25
12.70
+10
15.45
-3.215
Free
L
Cationic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek-293 T Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
pEGFP-nef-vpr-gp160-p25
Cellular uptake of 23.20 ± 0.81%
In vitro
CCSCCCCCC
Additional Detail Fields 1 fields
CCSCCCCCC