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Peptide record

TPDB61444

FAM-CGY scrambled 2 Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61444
FAM-CGY scrambled 2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: NanoLigand Carriers (NLCs) , nanofibres
Sequence
CGYRPVHNIRGHGAPG
Physicochemical Analysis
C72H111N27O19S1
DEQLKMFSTW
G
1690.90
9.90
4
0
4
+2
3.31
-0.750
48.75
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
88.12
3
Residue Composition
number
1
A
2
R
1
N
0
D
1
C
0
E
0
Q
4
G
2
H
1
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 4 H: 2 I: 1 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
16
C72H111N27O19S1
1690.90
9.90
+2
3.31
-0.750
Free
NanoLigand Carriers (NLCs) , nanofibres
L
Amphiphilic
Linear
Free
N[C@@H](CS)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

hCMEC/D3 Cells, MCF-7 Cells , Ebm-2 And MCF-10A Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Protein derived
5-FAM at N terminal
Low cellular uptake than FAM-CGY
In vitro
CCSCCCCCSSCCCC
Additional Detail Fields 1 fields
CCSCCCCCSSCCCC