Back to search

Peptide record

TPDB61432

Tat-linked CPP Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB61432
Tat-linked CPP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: AuNPs coated with cysteamine
Sequence
CGRKKRWWPQRWWRWWRPPQ
Physicochemical Analysis
C138H191N45O23S1
ANDEHILMFSTYV
W
2880.38
12.58
7
0
6
+7
-2.79
-2.270
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
33000
1145.68
3
Residue Composition
number
0
A
5
R
0
N
0
D
1
C
0
E
2
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
3
P
0
S
0
T
6
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 3 S: 0 T: 0 W: 6 Y: 0 V: 0
Chemical Descriptors
20
C138H191N45O23S1
2880.38
12.58
+7
-2.79
-2.270
Free
AuNPs coated with cysteamine
L
Cationic
Linear
Free
N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

ARPE-19 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
siRNA
In vitro
CCSCCCCCTHHHHTTCCCCC
Additional Detail Fields 1 fields
CCSCCCCCTHHHHTTCCCCC