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Peptide record

TPDB61405

M918(C-S) Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB61405
M918(C-S)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
CGGMVTVLFRRLRIRRASGPPRVRV-NH2
Physicochemical Analysis
C123H218N46O28S2
NDEQHKWY
R
2853.50
12.80
7
0
10
+7
3.95
0.020
97.20
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
7
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
1
I
2
L
0
K
1
M
1
F
2
P
1
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 0 M: 1 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
25
C123H218N46O28S2
2853.50
12.80
+7
3.95
0.020
Amidation
L
Linear
Free
N[C@@H](CS)C(=O)NCC(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HT-29-luc cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
PNA
Endocytosis
In vitro
CCCCTTTHHHHTSCCCCSSCCCCCC
Additional Detail Fields 1 fields
CCCCTTTHHHHTSCCCCSSCCCCCC