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Peptide record

TPDB61402

sgRNA-CPP Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB61402
sgRNA-CPP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
CGGGRRRRRRRRRLLLL
Physicochemical Analysis
C87H168N44O18S1
ANDEQHIKMFPSTWYV
R
2150.63
12.94
9
0
4
+9
4.84
-1.412
91.76
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
9
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C87H168N44O18S1
2150.63
12.94
+9
4.84
-1.412
Free
L
Cationic
Linear
Free
N[C@@H](CS)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HEK293T cells, HeLa cell, NCCIT cell line, human dermal fibroblast cells and The H9 human embryonic stem

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Nucleic acid (sgRNA)
Higher uptake efficiency
In vitro
CCCSCGGGGGGTSCCCC
Additional Detail Fields 1 fields
CCCSCGGGGGGTSCCCC