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Peptide record

TPDB61396

TAT Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB61396
TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, Peptipedia, and PerseuCPP, with an available 3D structural model.
C-terminal: Conjugation with nanoparticle N-terminal: Conjugation with rhodamine B
Sequence
CGGGGYGRKKRRQRRR
Physicochemical Analysis
C75H135N37O19S1
ANDEHILMFPSTWV
R
1891.19
12.41
8
0
1
+8
6.29
-2.444
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
78.79
3
Residue Composition
number
0
A
6
R
0
N
0
D
1
C
0
E
1
Q
5
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 5 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
16
C75H135N37O19S1
1891.19
12.41
+8
6.29
-2.444
Conjugation with nanoparticle
L
Cationic
Linear
Conjugation with rhodamine B
N[C@@H](CS)C(=O)/N=C/C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

New Zealand white rabbits
New Zealand white rabbits

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Nanoparticle
In vivo
CBSSSBCTTGGGSCCC
Additional Detail Fields 1 fields
CBSSSBCTTGGGSCCC